Ibuprofen can cause infertility in men, study says

Ibuprofen can cause infertility in men, study says

Ibuprofen may be linked to male infertility, a study has found, and although the effects were reversible the long-term effects are unknown.

A new study has found that men who take about 1200 milligrams of Ibuprofen a day experience hormonal imbalances that are associated with infertility. The common painkiller was found to depress testosterone production, causing study participants to develop a condition called "compensated hypogonadism".

"We normally see this condition in elderly men, so it raises an alarm", study co-author Bernard Jégou of the French National Institute of Health and Medical Research, told The Guardian.

The problem ranges worldwide: The World Health Organization says that one of every four couples spends at least five years unsuccessfully trying to get pregnant.

"The effects were very mild even after six weeks of regular consumption of ibuprofen, which is longer than is usually recommended in practice, so this data should not concern men who occasionally take ibuprofen for pain relief", Ali Abbara, Imperial College London's senior clinical lecturer in endocrinology, told Forbes.

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Dr Allan Pacey of the University of Sheffield said that the effects of over the counter painkillers such as Ibuprofen has been of increasing interest in recent years. Ask the average person whether ibuprofen is risky and they'll likely say it is safe when used properly, but that may not be true. This is the hormone that's secreted by the pituitary gland and stimulates the production of testosterone which plays important role in fertility.

14 of them were given daily doses of Ibuprofen, which professional and amateur athletes take.

Fortunately, the disorder related to ibuprofen use is totally reversible over a short period of time - as it was during the study. "We are concerned about it, particularly for healthy people who don't need to take these drugs". The findings are newly published in the journal Proceedings of the National Academy of Sciences.

The good news is that the problems required multiple weeks of constant ibuprofen use, so there's no indication that handling the odd muscle ache or hangover with ibuprofen will cause problems. But, don't worry, if you just want to tiresome the pain of a minor ankle sprain for a week or two, Jégou says, "it is sure that these effects are reversible". Until now, it has been primarily linked to adverse effects such as gastrointestinal bleeding, cardiovascular disorders and kidney damage.

The authors of the study have reportedly said that the drug disrupts male hormones and increases the likelihood that the affected male babies would be born with congenital malformations.

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