Researchers Develop Quick, Easy Test To Detect Cancer From Blood

Researchers Develop Quick, Easy Test To Detect Cancer From Blood

This test is still in development, and it draws a radical new approach to cancer detection that could make routine screening a straightforward procedure for doctors.

The research team disclosed that the test would detect about 90 in 100 cases of cancer. He said that they initially believed that each cancer would need a separate test for detection.

"This unique nano-scaled DNA signature appeared in every type of breast cancer we examined, and in other forms of cancer including prostate, colorectal and lymphoma", said Abu Sina, from the University of Queensland.

The sign of healthy cells is marked by the patterning of their DNA with molecules called methyl groups.

The new study focused on the "epigenome", or chemical modifications to DNA that turn genes "on" or "off".

Normal DNA has a large number of methyl "marks" in the affected cells of such "labels" are very small and are located at specific sites. The paper, titled "Epigenetically reprogrammed methylation landscape drives the DNA self-assembly and serves as a universal cancer biomarker", appeared December 4 in the journal Nature Communications. They were able to identify that the pattern creates a huge impact on the DNA's chemistry, leading the healthy and cancerous cells to behave differently in the water.

The discovery was made by a medical research team in Queensland.

Professor Matt Trau Dr. Abu Sina and Doctor Laura Carrascosa
Professor Matt Trau Dr. Abu Sina and Doctor Laura Carrascosa

Gold nanoparticles produced by laser ablation in heavy water. These complex structures depending upon the epigenetic pattern would then stick to gold nanoparticles used for the test.

The new method looks for differences in the genetic code of cancerous and healthy cells, the newspaper said.

Sina said: "It works for tissue-derived genomic DNA and blood-derived circulating free DNA".

"We certainly don't know yet whether it's the Holy Grail for all cancer diagnostics". He added that larger studies are needed to evaluate the accuracy of the test, as well as whether it could be useful for patients, compared with existing tests. But considering the results, he noted it could be helpful in detecting cancer easily, rather than conducting invasive procedures. As of 2018, there are more than 200 types of cancer. A universal cancer test would not be precise enough to pinpoint the location or size of a tumour, but would give doctors a swift answer to the question: does this patient have cancer?

Scientists have developed a cheap and simple test that can detect malignancy in 10 minutes.

Cancer blood tests became possible after scientists realised the importance of DNA released when cancer cells die, which is carried in the bloodstream.

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